Fumiyoshi Yamashita Selected Research

catalase-polyethylene glycol

9/2013	Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice.
2/2012	Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice.
12/2010	Improvement of insulin resistance by removal of systemic hydrogen peroxide by PEGylated catalase in obese mice.
7/2009	Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase.
11/2006	PEGylated catalase prevents metastatic tumor growth aggravated by tumor removal.
1/2006	Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase.
11/2004	Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells.
5/2002	Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice.

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Fumiyoshi Yamashita Research Topics

Disease

48	Neoplasms (Cancer) 11/2020 - 04/2002
19	Neoplasm Metastasis (Metastasis) 09/2013 - 04/2002
12	Melanoma (Melanoma, Malignant) 07/2020 - 11/2004
5	Inflammation (Inflammations) 11/2014 - 02/2007
5	Carcinoma (Carcinomatosis) 08/2014 - 05/2002
4	Hepatocellular Carcinoma (Hepatoma) 04/2007 - 02/2003
3	Breast Neoplasms (Breast Cancer) 04/2019 - 08/2010
3	Reperfusion Injury 01/2016 - 01/2008
2	Adenocarcinoma 12/2019 - 08/2008
2	Adenocarcinoma of Lung 01/2016 - 01/2016
2	Acute Liver Failure (Fulminant Hepatic Failure) 04/2014 - 01/2006
2	Ischemia 07/2012 - 01/2008
2	Body Weight (Weight, Body) 05/2009 - 01/2004
2	Colonic Neoplasms (Colon Cancer) 09/2007 - 09/2006
2	Lung Neoplasms (Lung Cancer) 11/2006 - 02/2006
1	Polymorphic catecholergic ventricular tachycardia 01/2022
1	Drug-Related Side Effects and Adverse Reactions 09/2021
1	Communicable Diseases (Infectious Diseases) 11/2020
1	Hyperthermia 07/2020
1	HIV Infections (HIV Infection) 09/2019

Drug/Important Bio-Agent (IBA)

18	Liposomes (Liposome)IBA 11/2014 - 04/2002
12	CatalaseIBA 02/2012 - 05/2002
11	DNA (Deoxyribonucleic Acid)IBA 11/2014 - 07/2007
8	Peptides (Polypeptides)IBA 04/2019 - 04/2006
8	catalase-polyethylene glycolIBA 09/2013 - 05/2002
8	Firefly LuciferasesIBA 09/2013 - 11/2004
7	Pharmaceutical PreparationsIBA 04/2019 - 09/2006
7	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2016 - 11/2004
7	LuciferasesIBA 09/2013 - 11/2004
7	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 09/2013 - 01/2006
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 11/2006
6	CytokinesIBA 11/2014 - 09/2003
5	SolutionsIBA 04/2019 - 09/2007
5	NF-kappa B (NF-kB)IBA 01/2014 - 02/2007
4	Dendrimers (Dendrons)IBA 01/2016 - 12/2006
4	LipidsIBA 11/2014 - 04/2006
4	LipopolysaccharidesIBA 11/2014 - 06/2006
4	DNA VaccinesIBA 11/2014 - 07/2007
4	Mannose (D-Mannose)IBA 11/2014 - 04/2011
4	Small Interfering RNA (siRNA)IBA 09/2014 - 07/2012
4	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2014 - 02/2006
3	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2019 - 11/2014
3	Indicators and Reagents (Reagents)IBA 07/2018 - 11/2004
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2014
3	Alanine Transaminase (SGPT)IBA 01/2016 - 01/2008
3	Messenger RNA (mRNA)IBA 01/2014 - 07/2006
3	EmulsionsIBA 05/2009 - 09/2005
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2006 - 09/2003
2	diazonaphthalenedisulfonic acid (NDS)IBA 07/2020 - 12/2019
2	LigandsIBA 01/2017 - 09/2006
2	Amino Acids FDA Link 01/2016 - 08/2010
2	Lysine (L-Lysine)FDA Link 01/2016 - 12/2006
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016 - 09/2015
2	Sulfhydryl Compounds (Thiols)IBA 01/2016 - 04/2014
2	Cysteine (L-Cysteine)FDA Link 01/2016 - 09/2006
2	Heparin (Liquaemin)FDA LinkGeneric 11/2014 - 11/2014
2	AntigensIBA 11/2014 - 07/2007
2	A-Form DNA (A-DNA)IBA 11/2014 - 04/2011
2	Carbon Nanotubes (Carbon Nanotube)IBA 08/2014 - 01/2014
2	Bovine Serum AlbuminIBA 04/2014 - 01/2008
2	EnzymesIBA 02/2012 - 05/2002
2	Therapeutic UsesIBA 12/2009 - 09/2003
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2009 - 01/2008
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2009 - 01/2008
2	HydrogelsIBA 07/2009 - 09/2007
2	MicellesIBA 05/2009 - 12/2005
2	Transcription Factors (Transcription Factor)IBA 08/2008 - 02/2007
2	Lipid PeroxidesIBA 01/2008 - 11/2006
2	Superoxide DismutaseIBA 01/2008 - 06/2006
2	ethylenediamine (ethylenediamine dihydroiodide)FDA Link 09/2007 - 05/2007
2	lysyl- arginyl- threonyl- glycyl- glutaminyl- tyrosyl- lysyl- leucyl- cysteineIBA 06/2007 - 09/2006
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 06/2007 - 09/2006
2	1,2- dioleoyloxy- 3- (trimethylammonium)propaneIBA 11/2006 - 02/2006
2	CholesterolIBA 11/2006 - 02/2006
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 01/2022
1	propylene (propene)IBA 09/2021
1	tetrafluoroethylene (tetrafluoroethene)IBA 09/2021
1	Elastomers (Elastomer)IBA 09/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 07/2020
1	NucleosidesIBA 09/2019
1	Anti-Retroviral Agents (Antiretroviral Agents)IBA 09/2019
1	Reverse Transcriptase InhibitorsIBA 09/2019
1	Protease Inhibitors (Protease Inhibitor)IBA 09/2019
1	IntegrasesIBA 09/2019
1	Paclitaxel (Taxol)FDA LinkGeneric 04/2019
1	Radioisotopes (Radionuclides)IBA 07/2018
1	E-SelectinIBA 01/2017
1	APTIBA 01/2016
1	CationsIBA 01/2016

Therapy/Procedure

15	Therapeutics 11/2020 - 12/2005
10	Intravenous Injections 11/2009 - 09/2003
4	Immunotherapy 11/2014 - 03/2008
3	Precision Medicine 07/2020 - 06/2015
3	Drug Therapy (Chemotherapy) 09/2019 - 03/2008
3	Intraperitoneal Injections 04/2014 - 01/2006
3	Intravenous Administration 03/2009 - 09/2003
2	Injections 09/2013 - 02/2012
2	Intranasal Administration 01/2012 - 01/2010
2	Operative Surgical Procedures 01/2008 - 11/2006
1	Lab-On-A-Chip Devices 09/2021